Hard core data geeks have a chance to get in on the ground level of a start-up at the Department of Commerce, the Commerce Data Service.
The National O*NET Center has released version of the 20.1 O*NET Database. This version contains tables that were available previously as supplemental files. See the NCSC's O*NET 20.1 page
for more info and downloads.
The Census Bureau's Business Dynamics Statistics
provide annual statistics on establishments, firm startups, and job creation and job loss for states and metropolitan areas. Data are available for 1976-2013.